Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.
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#335: Gene Editing with Python
Gene therapy holds the promise to permanently cure diseases that have been considered life-long challenges. But the complexity of rewriting DNA is truly huge and lives in its own special kind of big-data world. On this episode, you'll meet David Born, a computational biologist who uses Python to help automate genetics research and helps move that work to production. Links from the show David on Twitter: @Hypostulate Beam Therapeutics: beamtx.com AWS Cloud Development Kit: aws.amazon.com/cdk Jupyter: jupyter.org $1,279-per-hour, 30,000-core cluster built on Amazon EC2 cloud: arstechnica.com Luigi data pipelines: luigi.readthedocs.io AWS Batch: aws.amazon.com/batch What is CRISPR?: wikipedia.org SUMMIT supercomputer: olcf.ornl.gov/summit Watch this episode on YouTube: youtube.com Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Shortcut Talk Python Training AssemblyAI
#334: Microsoft Planetary Computer
On this episode, Rob Emanuele and Tom Augspurger join us to talk about building and running Microsoft's Planetary Computer project. This project is dedicated to providing the data around climate records and the compute necessary to process it with the mission of help use all understand climate change better. It combines multiple petabytes of data with a powerful hosted Jupyterlab notebook environment to process it. Links from the show Rob Emanuele on Twitter: @lossyrob Tom Augspurger on Twitter: @TomAugspurger Video at example walkthrough by Tom if you want to follow along: youtube.com?t=2360 Planetary computer: planetarycomputer.microsoft.com Applications in public: planetarycomputer.microsoft.com Microsoft's Environmental Commitments Carbon negative: blogs.microsoft.com Report: microsoft.com AI for Earth grants: microsoft.com Python SDK: github.com Planetary computer containers: github.com IPCC Climate Report: ipcc.ch Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Shortcut Talk Python Training AssemblyAI
#333: State of Data Science in 2021
We know that Python and data science are growing in lock-step together. But exactly what's happening in the data science space in 2021? Stan Seibert from Anaconda is here to give us a report on what they found with their latest "State of Data Science in 2021" survey. Links from the show Stan on Twitter: @seibert State of data science survey results: know.anaconda.com A Python Data Scientist’s Guide to the Apple Silicon Transition: anaconda.com Numpy M1 Issue: github.com A Python Developer Explores Apple's M1 (Michael's video): youtube.com Watch this episode on YouTube: youtube.com Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Shortcut Masterworks.io AssemblyAI Talk Python Training
#332: Robust Python
Does it seem like your Python projects are getting bigger and bigger? Are you feeling the pain as your codebase expands and gets tougher to debug and maintain? Patrick Viafore is here to help us write more maintainable, longer-lived, and more enjoyable Python code. Links from the show Pat on Twitter: @PatViaforever Robust Python Book: oreilly.com Typing in Python: docs.python.org mypy: mypy-lang.org SQLModel: sqlmodel.tiangolo.com CUPID principles @ relevant time: overcast.fm Stevedore package: docs.openstack.org Watch this episode on YouTube: youtube.com Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Shortcut Masterworks.io AssemblyAI Talk Python Training
#331: Meet the Python Developer in Residence: Lukasz Langa
Python is a technology and community built upon the goodwill and volunteer time of 1,000s of contributors from the core devs inside CPython to the authors of 100,000s of external packages on PyPI. Until recently, the only full time folks have been at the PSF doing very important work but that work has been largely outside of CPython the technology. In July, 2021, the PSF created the Python Developer in Residence position. The first person in that role is Łukasz Langa and he's here to tell us how it's going and how it will benefit Python at large. Links from the show Łukasz Langa on twitter: @llanga Black: github.com/psf/black CPython PRs: github.com Weekly reports: lukasz.langa.pl Visionary Sponsors: python.org/psf/sponsorship/sponsors What do you get when you sponsor the PSF?: www.python.org/sponsors/application Brett Canon's PyCascades talk: youtube.com Django fellowship program: djangoproject.com Lukasz's prior episodes: Gradual Typing of Production Applications: talkpython.fm/151 Dive into CPython 3.8 and beyond: talkpython.fm/214 Python Language Summit 2018: talkpython.fm/179 Watch this episode on YouTube: youtube.com Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Talk Python Training AssemblyAI
#330: Apache Airflow Open-Source Workflow with Python
If you are working with data pipelines, you definitely need to give Apache Airflow a look. This pure-Python workflow framework is one of the most popular and capable out there. You create your workflows by writing Python code using clever language operators and then you can monitor them and even debug them visually once they get started. Stop writing manual code or cron-job based code to create data pipelines check out Airflow. We're joined by three excellent guests from the Airflow community: Jarek Potiuk, Kaxil Naik, and Leah Cole. Links from the show Jarek Potiuk: linkedin.com Kaxil Naik: @kaxil Leah Cole: @leahecole Airflow site: airflow.apache.org Airflow on GitHub: github.com Airflow community: airflow.apache.org UI: github.com Helm Chart for Apache Airflow: airflow.apache.org Airflow Summit: airflowsummit.org Astronomer: astronomer.io Astronomer Registry (Easy to search for official and community Providers): registry.astronomer.io REST API: airflow.apache.org Contributing: github.com Airflow Loves Kubernetes talk: airflowsummit.org Watch this episode on YouTube: youtube.com Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Talk Python Training AssemblyAI
#329: Geekout: Renewable Energy
We're back with another GeekOut episode. Richard Campbell, a developer and podcaster who also dives deep into science and tech topics, is back for our third GeekOut episode. This time around, we're diving into renewable energy, energy storage, and just what do we do to keep the lights on with our frying our beloved Earth? Links from the show Richard on Twitter: @richcampbell IEA report 2021: iea.org Flywheel storage: blogspot.com Crane storage: eni.com Pumped hydro storage: eurekalert.org Tesla battery utility-scale: tesla.com The US’s largest solar farm is canceled because Nevada locals don’t want to look at it: electrek.co DEVintersection conference (run by Richard): devintersection.com .NET Rocks Podcast (Richard's a cohost, many geekout episodes): dotnetrocks.com Prior Geekouts on Talk Python #276: Geekout: Life in the solar system and beyond: talkpython.fm #253: Moon base geekout: talkpython.fm Watch this episode on YouTube: youtube.com Episode transcripts: talkpython.fm ---------- Stay in touch with us ---------- Subscribe on YouTube (for live streams): youtube.com Follow Talk Python on Twitter: @talkpython Follow Michael on Twitter: @mkennedy Sponsors Talk Python Training AssemblyAI
#328: Piccolo: A fast, async ORM for Python (updated)
See the full show notes for this episode on the website at talkpython.fm/328.
#327: Little Automation Tools in Python
See the full show notes for this episode on the website at talkpython.fm/327.
#326: Building Desktop Apps with wxPython
See the full show notes for this episode on the website at talkpython.fm/326.
#325: MicroPython + CircuitPython
See the full show notes for this episode on the website at talkpython.fm/325.
#324: Gatorade-powered Python APIs
See the full show notes for this episode on the website at talkpython.fm/324.
#323: Best practices for Docker in production
See the full show notes for this episode on the website at talkpython.fm/323.
#322: A path into data science
See the full show notes for this episode on the website at talkpython.fm/322.
#321: HTMX - Clean, Dynamic HTML Pages
See the full show notes for this episode on the website at talkpython.fm/321.