The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.
Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity | Episode 85
My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan, healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work, body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health.
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For the full show notes, visit hubermanlab.com
Timestamps
(00:00:00) Assessing Health Status & Improving Vitality
(00:02:51) Momentous Supplements
(00:03:46) Thesis, InsideTracker, Helix Sleep
(00:07:29) Lifespan: Bloodwork & Biomarkers Testing, The “4 Horseman of Disease”
(00:11:51) Healthspan: Functional Testing, Cognitive & Emotional States
(00:13:59) Blood Testing: Best Frequency
(00:16:01) DEXA Scan: Lean Mass & Fat, Bone Mineral Density & Osteoporosis
(00:22:33) Bone Mineral Density & Age-Related Decline, Strength Training, Corticosteroids
(00:29:24) Osteopenia & Osteoporosis Diagnosis, Strength Training
(00:31:03) AG1 (Athletic Greens)
(00:32:16) Back-casting: Defining Your “Marginal Decade”
(00:38:31) All-Cause Mortality: Smoking, Strength, VO2 max
(00:44:43) Attia’s Rule of Supplementation, “Centenarian Decathlete” Physical Goals
(00:49:24) Importance of Exercise, Brain Health, MET hours
(00:55:23) Nicotine & Cognitive Focus
(01:03:12) Menstruation, PMS & Menopause
(01:10:10) Hormone Replacement Therapy, Menopause & Breast Cancer Risk
(01:22:06) Estrogen, Progesterone & Testosterone Therapies in Women
(01:26:35) Hormone Replacement Therapy in Men, SHBG & Testosterone, Insulin
(01:37:23) Clomid, Pituitary, Testosterone & Cholesterol, Anastrozole, HCG
(01:47:46) Fadogia Agrestis, Supplements, Rapamycin
(01:52:06) Testosterone Replacement Therapy & Fertility
(01:59:26) Total Testosterone vs. Free Testosterone
(02:02:51) Cholesterol & Dietary Cholesterol, Saturated Fat, LDL & HDL, Apolipoprotein B
(02:17:42) Apolipoprotein B, Diet, Statins & Other Cholesterol Prescriptions
(02:25:15) Cardiovascular Disease, Age & Disease Risk
(02:28:53) Peptides, Stem Cells, BPC157, PRP (Platelet-Rich Plasma), Injury Rehabilitation
(02:37:40) Metabolomics & Exercise
(02:40:44) GLP-1 & Weight Loss
(02:47:06) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips
Title Card Photo Credit: Mike Blabac