The Huberman Lab Podcast discusses neuroscience: how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health. We also discuss existing and emerging tools for measuring and changing how our nervous system works. Dr. Andrew Huberman is a tenured Professor of Neurobiology and Ophthalmology at Stanford School of Medicine. His laboratory studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance. For more than 20 years, Dr. Huberman has consistently published original research findings and review articles in top-level peer-reviewed journals, including Nature, Science, Cell, Neuron, and Current Biology. He is a regular member of several National Institutes of Health review panels and a Fellow of the McKnight Foundation and the Pew Charitable Trusts. Dr. Huberman regularly consults for technology development companies, professional athletic organizations, and various units of U.S. and Canadian Special Operations.
Essentials: How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried
In this Huberman Lab Essentials episode, my guest is Dr. Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and expert in female hormone health. We discuss the key biomarkers women should track at each stage of life and how cortisol, thyroid hormone, estrogen, progesterone, and testosterone shape energy, mood, metabolism, and long-term disease risk. We also discuss PCOS, the risks and benefits of oral contraceptives, and the shift in brain metabolism that begins in perimenopause. Dr. Gottfried explains actionable tools for hormone and micronutrient testing, nutrition, stress management, and cardiometabolic screening that women can use at any age.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
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Timestamps
(00:00:00) Female Hormone Health
(00:00:24) Family History, Intergenerational Trauma; Endometriosis, Fibroids, PCOS
(00:01:31) Biomarkers by Decade; Teens & Cortisol; 20s & Sex Hormones
(00:03:35) Tool: Hormone Test Timing; Micronutrient Testing, Magnesium
(00:05:41) Sponsor: LMNT
(00:07:17) Tool: Smoothies, Greens Powders & Microbiome
(00:08:12) Nutrient Panels, Antioxidants, B Vitamins, Glutathione
(00:09:34) Constipation, Thyroid Dysfunction; Trauma & Female Physiology
(00:11:50) Tools: Reduce Perceived Stress, Meditation, Yoga, Breathwork
(00:13:30) Opportunities by Decade; Androgens & Testosterone Decline
(00:14:50) PCOS, Diagnostic Criteria, Hirsutism, Cardiometabolic Risk
(00:17:10) Insulin & Glucose; Tool: Continuous Glucose Monitors
(00:18:05) Democratizing Health Data
(00:18:52) Sponsor: AG1
(00:20:07) Longevity "Don’ts"; Chronic Cardio & Cortisol; Tool: Adaptive Exercise
(00:22:46) Oral Contraceptives, Benefits & Ovarian Cancer Risk
(00:24:27) Ovarian Cancer Symptoms, Bloating, CA-125
(00:25:51) Oral Contraceptive Risks, Progestins, Inflammation; SHBG & Testosterone
(00:29:08) Clitoral Shrinkage; Tools: Alternatives for Painful Periods
(00:30:14) Sponsor: Eight Sleep
(00:31:32) Menopause & Perimenopause; 30s Hormonal Baseline
(00:33:07) Female Brain, Cerebral Hypometabolism & Alzheimer’s Risk
(00:35:02) Slow Brain Energy, Hormone Therapy; Hot Flashes as Biomarkers
(00:36:54) Tool: Coronary Artery Calcium Score
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